What is the drug "Amoxiclav"? What helps this tool? The answers to these and other questions you will learn from the materials of this article. We will tell you about how much this medicine costs, in what form it is produced and whether it can be combined with alcohol.
The drug "Amoxiclav" (1000 mg) contains active substances such as potassium salt of clavulanic acid and amoxicillin trihydrate. Currently, it is produced in the following forms:
Amoxiclav tablets (1000 mg) are packed in aluminum blisters and cardboard packs, respectively.
Powder for the preparation of the suspension can be purchased in bottles of dark glass. A measuring spoon is also attached to the drug.
As for the injection form, it is available in bottles of 1.2 and 0.6 g, which are placed in cardboard packs.
How does the drug "Amoxiclav" work? Instruction, reviews report that the combination of clavulanic acid and amoxicillin is unique in its kind.
Amoxicillin causes the death of bacteria, binding themsurface receptors. However, most microorganisms have learned to destroy this antibiotic substance through a beta-lactamase enzyme. The activity of this enzyme is able to reduce clavulanic acid. Due to this effect, suspension, injection and Amoxiclav tablets (1000 mg) are used to treat many infectious diseases.
What are the properties of antibiotics? "Amoxiclav" (1000 mg) kills even those strains of bacteria that have already shown resistance to amoxicillin.
The preparation in question has a pronouncedbactericidal and bacteriostatic effects on all types of echinococcus, streptococcus and listeria (except methicillin-resistant strains). Also, Gram-negative bacteria such as brucella, Bordetella, Gardnerella, Salmonella, Klebsiella, Proteus, Moraxella, Clostridium, Shigella and others are sensitive to this drug.
Whether it is possible to accept a preparation "Amoksiklav" (1000mg) with food? Regardless of food, this medication is well absorbed from the intestine. Its highest concentration is achieved after a lapse of 60 minutes. It has a high rate and volume of distribution in the body (in tonsils, lungs, synovial and pleural fluids, fat and muscle tissues, the prostate gland, middle ear and sinuses of the nose).
In the mother's milk, this drug comes in small quantities.
Amoxicillin is partially destroyed in the body, and clavulanic acid is extensively metabolized.
Drug is withdrawn through the kidneys, as well as the lungs and intestines. The half-life period is 90 minutes.
The antibiotic in question is prescribed for the treatment of various infectious diseases:
Whether there are contraindications to antibiotic application"Amoxiclav"? Treatment with this agent is not carried out with impaired liver function and jaundice (cholestatic), as well as hypersensitivity to medication substances or to all penicillins.
This drug with extreme caution is prescribed in the presence of allergies to cephalosporins, insufficiency of liver function, pseudomembranous colitis and severe renal dysfunction.
In patients with lymphatic leukemia or mononucleosis, which has been prescribed ampicillin, a rash can appear as erythematous. With such a reaction, the antibiotic should be withdrawn.
The drug "Amoxiclav" can be administered to patients in different ways. The method of its application depends on the weight and age of the patient, the state of the liver and kidneys, as well as the severity of the infection.
The most optimal time to usethis medicine is the beginning of the meal. The duration of therapy with this drug is 6-14 days. Use the drug for longer than the specified period is prohibited.
Children under the age of 12 years,antibiotic is prescribed at the rate of 40 mg per kg of body weight per day. Adolescents, whose weight is more than 40 kg, the drug is given in the same dosage as the adult.
Adults take 375 mg tablets everyeight hours, and the drug 625 mg every 12. In severe infections, the patient is recommended to take a medication at a dose of 625 mg (every eight hours) or 1000 mg (every 12 hours).
Doctors emphasize that tablets "Amoxiclav" may differ in the number of active ingredients. Therefore, it should be borne in mind that it is forbidden to replace the dose of 625 mg with two doses of 375 mg.
For the treatment of odontogenic infections, the following regimen is used: the drug at a dosage of 375 mg is administered every eight hours, and at a dose of 625 mg every 12 hours.
If you want to take the medicine to patients with kidney disease, then necessarily take into account the creatinine content in the urine. People with liver pathologies should be monitored continuously.
How to give a small child a drug"Amoxiclav"? Suspension, the price of which is not very high, is prescribed for babies up to 3 months. The dose of this medication is determined using a measuring spoon or pipette. For each kg of the weight of the child must account for 30 mg of amoxicillin. Take medication twice a day.
For children older than 3 months with an average and mild disease, the drug is prescribed at a rate of 20 mg per kg of weight.
How in case of severe infections do they use "Amoxiclav"? Suspension (the price of the medication will be indicated below) to children is prescribed in the amount of 40 mg per kg of weight. The same dose is also used for the treatment of deep infections (for example, inflammation of the middle ear, bronchitis, sinusitis, pneumonia, etc.).
The maximum daily dose of amoxicillin to children is 45 mg / kg, and adults - 6 grams. As for clavulanic acid, it can be taken per day not more than 10 mg / kg for children and 600 mg for adults.
As a rule, the drug "Amoxiclav" is transferredgood enough. Although in some cases, side effects occur in the elderly and those patients who take medication for a long time.
Most often, unwanted reactions occur during or after the completion of therapy. Although sometimes their development is observed and after a few weeks after treatment:
It is undesirable to combine "Amoxiclav" and the means of indirect anticoagulants, since this can contribute to an increase in prothrombin time.
This drug increases the toxicity of Metatrexate.
The interaction of allopurinol and "Amoxiclav" causes the risk of occurrence of exanthema.
It is forbidden to prescribe medication together with macrolides or tetracyclines, as well as with sulfonamides due to a decrease in its effectiveness.
You can not combine rifampicin and amoxicillin, since these are antagonist drugs. Their joint intake weakens the antibacterial effect of both.
Taking this medication reduces the effectiveness of oral contraceptives.
It should also be noted that the drug "Amoxiclav" (1000) and alcohol combined is prohibited because of the possible increase in adverse reactions.
Synonyms of this drug are: "Klavocin", "Augmentin" and "Moxicraft". As for the analogs, they are:
How much is the antibiotic "Amoxiclav"? Its price depends on the form of release. Tablets (1000 mg) can be purchased for 480 rubles, suspension - for 280, and lyophilized powder for injection - for 180.
According to patients' reviews, this medicationis an effective drug that is used to treat a variety of infectious diseases. When taking medication for the therapy of respiratory ailments, relief comes on the third day.
Also, the drug is actively prescribed for the treatment of genito-urinary infections.
In addition to positive feedback about this antibiotic,patients leave and negative messages. According to them, the drug "Amoxiclav" causes many side effects, which manifest themselves in the form of nausea, diarrhea and vomiting.
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